These talks take a new, fresh perspective while exploring the epidemic of addiction.

As of 2021, more than 36 million people were estimated to be experiencing substance use disorder. This condition spans a spectrum of patterned drug use that causes issues in a person’s life, with substance addiction at the more severe end. Why are some people more susceptible to addiction, and why can it be so difficult to treat? Judy Grisel tak...

In the 1980s and 90s, pharmaceutical companies began to market opioid painkillers aggressively, while actively downplaying their addictive potential. The number of prescriptions skyrocketed, and so did cases of addiction, beginning a crisis that continues today. What makes opioids so addictive? Mike Davis explains what we can do to reverse the s...

What do Tourette syndrome, heroin addiction and social media obsession all have in common? They converge in an area of the brain called the striatum, says neuroscientist Rachel Wurzman -- and this critical discovery could reshape our understanding of the opioid crisis. Sharing insights from her research, Wurzman shows how social isolation contri...

Could CBD, a chemical compound found in the cannabis plant, help treat opioid addiction? Neuroscientist Yasmin Hurd discusses why current treatment strategies, such as methadone, aren't enough to end the opioid epidemic -- and shares how CBD could help reduce the cravings and anxiety associated with drug use and relapse, potentially providing a ...

Tobacco use remains the leading cause of preventable disease and death in the United States, killing more people each year than alcohol, AIDS, car accidents, illegal drugs, murder and suicide combined. Follow health policy expert Mitch Zeller into the murky depths of the tobacco industry as he details the sordid history of nicotine addiction -- ...

Less than an hour after scrambling out the back door of the Columbine High School library on April 20, 1999, Austin Eubanks was lying in a hospital bed, medicated on a variety of painkillers. That was the beginning of a decade-long addiction that led to a profound realization about the current opioid epidemic: how we manage pain is both the prob...

Why do we still think that drug use is a law-enforcement issue? Making drugs illegal does nothing to stop people from using them, says public health expert Mark Tyndall. So, what might work? Tyndall shares community-based research that shows how harm-reduction strategies, like safe-injection sites, are working to address the drug overdose crisis.

Only one in nine people in the United States gets the care and treatment they need for addiction and substance abuse. A former Director of National Drug Control Policy, Michael Botticelli is working to end this epidemic and treat people with addictions with kindness, compassion and fairness. In a personal, thoughtful talk, he encourages the mill...

What really causes addiction -- to everything from cocaine to smart-phones? And how can we overcome it? Johann Hari has seen our current methods fail firsthand, as he has watched loved ones struggle to manage their addictions. He started to wonder why we treat addicts the way we do -- and if there might be a better way. As he shares in this deep...

Can we break bad habits by being more curious about them? Psychiatrist Judson Brewer studies the relationship between mindfulness and addiction -- from smoking to overeating to all those other things we do even though we know they're bad for us. Learn more about the mechanism of habit development and discover a simple but profound tactic that mi...

TikTok CEO Shou Chew dives into how the trend-setting video app and cultural phenomenon works — from what distinguishes its algorithm and drives virality to the challenges of content moderation and digital addiction. In a wide-ranging conversation with head of TED Chris Anderson, he tells stories about the TikTok creators he loves and digs into ...

These eye-opening talks call into question some of the popular misconceptions, fallacies and exaggerated rumors of modern civilization.

As Director of National Drug Control Policy, Michael Botticelli led the Obama Administration’s drug policy efforts to diminish the consequences of substance use through evidence-based prevention, treatment and recovery support services.

These talks will shake you awake to the world around you.

When a young woman texted with a heartbreaking cry for help, the organization responded by opening a nationwide Crisis Text Line for people in pain. Nearly 10 million text messages later, the organization is using the privacy and power of text messaging to help people handle addiction, suicidal thoughts, eating disorders, sexual abuse and more. ...

Can we call any economy "healthy" in the face of dwindling resources and growing inequality? What if we cut off our addiction to endless growth, and used a new compass for modern prosperity? One such compass is known as "doughnut economics," which aims to meet the needs of people without overshooting Earth's ecological limits. Explore how this m...

Pain is your body's signal that something isn't right. To help manage it, doctors often prescribe powerful opioids -- but they're not always the best option and can quickly lead to addiction. Illuminating the fine line between substance use and abuse, Dr. Jen Gunter explains what opioids do to your perception of pain, the risks they pose and the...

Neuroscientist Yasmin Hurd researches nonaddictive, efficacious treatments that use cannabidiol (CDB) to address the opioid epidemic.

E-cigarettes and vapes have exploded in popularity in the last decade, especially among youth and young adults -- from 2011 to 2015, e-cigarette use among high school students in the US increased by 900 percent. Biobehavioral scientist Suchitra Krishnan-Sarin explains what you're actually inhaling when you vape (hint: it's definitely not water v...

Through her nonprofit SeekHealing, Rachel Wurzman aims to reduce opioid overdose rates by building communities that are inherently resilient to addiction.

What a year! Here are the talks you enjoyed the most from 2015.

A handful of people working at a handful of tech companies steer the thoughts of billions of people every day, says design thinker Tristan Harris. From Facebook notifications to Snapstreaks to YouTube autoplays, they're all competing for one thing: your attention. Harris shares how these companies prey on our psychology for their own profit and ...

When you eat something loaded with sugar, your taste buds, your gut and your brain all take notice. This activation of your reward system is not unlike how bodies process addictive substances such as alcohol or nicotine -- an overload of sugar spikes dopamine levels and leaves you craving more. Nicole Avena explains why sweets and treats should ...

What are our screens and devices doing to us? Psychologist Adam Alter studies how much time screens steal from us and how they're getting away with it. He shares why all those hours you spend staring at your smartphone, tablet or computer might be making you miserable -- and what you can do about it.

Public libraries have always been about more than just books -- and their mission of community support has taken on new urgency during the current opioid epidemic. After witnessing overdoses at her library in Philadelphia, Chera Kowalski learned how to administer naloxone, a drug that reverses the effects of narcotics, and she's put it to use to...

At some point in our lives, almost every one of us will have our heart broken. Imagine how different things would be if we paid more attention to this unique emotional pain. Psychologist Guy Winch reveals how recovering from heartbreak starts with a determination to fight our instincts to idealize and search for answers that aren't there -- and ...

As a fire chief and first responder, Jan Rader has spent her career saving lives. But when the opioid epidemic hit her town, she realized they needed to take a brand-new approach to life-saving. In this powerful, hopeful talk, Rader shows what it's like on the front lines of this crisis -- and how her community is taking an unusual new approach ...

KC Davis offers a compassionate and practical approach to self and home care for those dealing with mental health, physical illness and hard seasons of life

Do you sometimes have your most creative ideas while folding laundry, washing dishes or doing nothing in particular? It's because when your body goes on autopilot, your brain gets busy forming new neural connections that connect ideas and solve problems. Learn to love being bored as Manoush Zomorodi explains the connection between spacing out an...